Further shRNA lines available (Sep 18, 2017)

Dear VDRC users,

The VDRC is continuing to create new shRNA and we have recently added more lines to extend our RNAi our collection.
See http://stockcenter.vdrc.at/control/library_rnai for the full list.

Your VDRC Team

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25th European Drosophila Research Conference in London, Sep 22-25, 2017 (Sep 17, 2017)

Dear VDRC users,

The VDRC will be exhibiting at the 25th European Drosophila Research Conference in London.
You are welcome to visit us to find out about our latest innovations and give us your feedback.

We look forward to seeing you there!

Your VDRC Team

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Vienna Tiles (VT) GAL4 Stock Pruning List - order by 30th Sep 2017 (Jul 11, 2017)

Dear VDRC users,

To streamline the VDRC stock collection, we will continue to maintain only 1000 Vienna Tiles (VT) GAL4 stocks, including those most frequently requested and those with sparser expression patterns in the adult brain.
The remaining ~7500 low-use VT GAL4 stocks will be discarded [list]. These will no longer be available for ordering after Sep 30th 2017, so if you need them, please order in good time - they will be gone forever after this date!

Your VDRC Team

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57th Annual Drosophila Research Conference in San Diego, March 29 - April 2, 2017 (Mar 20, 2017)

Dear VDRC users,

The VDRC is happy to attend the 57th Drosophila Research Conference in San Diego.
You will find us at booth # 214. You are welcome to visit us to find out about our latest innovations and give us your feedback.

We look forward to seeing you there!

Your VDRC Team

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"NEW" and "SIMILAR" tags added in search results (Jan 25, 2017)

We have made some changes to the way search results are displayed:

We've added the tag "NEW" to resources which have been recently added to the VDRC collection, to help you clearly distinguish them in the search results table.

The tag "SIMILAR" will appear when you search for a specific term and we wish to show you related resources. As an example, with the search term "33277" the search results will display the primary hit first (VDRC_ID 33277) and below it all related lines with the tag "SIMILAR", in this case 2 further resources matching the same CG number. If the search is more general e.g. with the search term "*10125", there can be more than one primary result from the search. In such a case, one primary result and its SIMILAR lines will be listed first, followed by the next primary result and its SIMILAR lines, with each related group separated by a solid line. Currently it is not possible to sort the SIMILAR lines, nor to filter them by library type, but we're working on it.

If the results are too confusing, we would suggest trying again with a more specific search term!

We would welcome your feedback on these changes. Please send any comments to office@vdrc.at.

Your VDRC Team

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VDRC website relaunch (Dec 15, 2016)

Dear VDRC users,

We have modernised our homepage (www.vdrc.at), not only to give it a fresh look, but also to make it even more user-friendly and to incorporate some new features.

These include:

  • Highlighting the most recently added resources
  • A regularly updated list of the most popular lines
  • Addition of links to FlyBase Reference Reports showing when the use of a specific line has been cited in publications
  • Improved search features
  • Ability to store lines in the shopping cart when you log out
  • Responsive web design for ease of use on desktops, tablets and phones

We would welcome your feedback and ideas for improvement and please do not hesitate to contact us if you find anything that does not work as it should.

Our thanks go to Barbara Wohlmuth and Thomas Micheler (Strategic Information Management Facility, VBCF) for realizing this project.

Your VDRC Team

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End of year shipping schedules (Nov 10, 2016)

Dear VDRC users,

This year we will be closed for shipping from 17th December 2016 until 9th January 2017. Past experience has shown that this is a poor time to ship stocks due to the cold weather, increased postal traffic and holiday closings. Please plan your orders accordingly.

The ordering deadline for guaranteed shipping before Christmas is 1st Dec, midnight CET, for small orders (100 items or less). The last shipping date for 2016 will be 16th Dec. Large orders and any orders placed after 1st Dec will be processed as soon as possible, but with no guarantee that they can be dispatched by 16th Dec.

Any orders not dispatched by 16th Dec will be put on hold until we begin shipping again on 9th Jan 2017. The website will be closed for ordering on 30th and 31st Dec 2016 and 1st Jan 2017.

We would like to thank you for your co-operation and custom throughout the whole year and wish you a happy festive time.

Your VDRC Team

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VDRC stockcenter offline 14.10.2016 to 17.10.2016 (Oct 11, 2016)

Dear VDRC users,

Due to moving of our central server infrastructure, placing orders will not be possible on Fri 14th October from 9:00 CET. We expect to be up and running again on Mon 17th Oct.
Thank you for your understanding.

We apologise for the inconvenience and thank you for your patience and understanding.

Your VDRC Team

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Potential payment problems (June 22, 2016)

Dear VDRC users,

Due to an issue with the SIX Payment System, which is beyond the control of the VDRC, you may be experiencing problems with ordering (https://www.six-payment-services.com/en/home.html#country=at). The SIX team ensure us that they are working on it urgently and hope to fix the problem as soon as possible. If your order fails, please try again later.

We apologise for the inconvenience and thank you for your patience and understanding.

Your VDRC Team

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New stocks added from Wasser lab (May 18, 2016)

Dear VDRC users,

Several lines from the private collection of Martin Wasser (Bioinformatics Institute, Singapore) are now publicly available through VDRC.

The collection consists of 15 lines which can be displayed by using the search term "wasser" or under "Browse the M. Wasser Stocks (MW-STOCK)" in the "Other Resources" section and includes a variety of mutant alleles, tagged constructs and reporters lines from the following publications:

Wasser M, Chia W. (2000)
The EAST protein of drosophila controls an expandable nuclear endoskeleton.
Nat Cell Biol. 2000 May;2(5):268-75.
PubMed 10806477

Chinta R and Wasser M (2012)
Three-dimensional segmentation of nuclei and mitotic chromosomes for the study of cell divisions in live Drosophila embryos.
Cytometry A. 2012 Jan;81(1):52-64. doi: 10.1002/cyto.a.21164. Epub 2011 Nov 8.
PubMed 22069299

Puah WC and Wasser M (2016)
Live imaging of muscles in Drosophila metamorphosis: Towards high-throughput gene identification and function analysis.
Methods. 2016 Mar 1;96:103-17. doi: 10.1016/j.ymeth.2015.09.028. Epub 2015 Oct 1.
PubMed 26431669

Kuleesha Y, Puah WC, Wasser M (2016)
A model of muscle atrophy based on live microscopy of muscle remodelling in Drosophila metamorphosis.
R Soc Open Sci. 2016 Feb 10;3(2):150517. doi: 10.1098/rsos.150517. eCollection 2016 Feb.
PubMed 26998322

When using these lines, please cite the appropriate Wasser publication and acknowledge the VDRC for providing the lines.

Your VDRC Team

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New stocks added from Harvey lab (May 11, 2016)

Dear VDRC users,

Control lines for the KK library, donated by Kieran Harvey (Peter MacCallum Cancer Centre, Melbourne, Australia) are now available. (For details see Vissers et al, Nat. Comm. (2016) : A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth).

The collection consists of 5 lines which can be displayed by using the search term "harvey":

An RNAi-toolkit stock (VDRC_ID 60101) where the landing sites at 40D and 30B in the KK library host strain have been separated by meiotic recombination. This line contains Gal4-responsive UAS repeats but no functional RNAi coding sequence at 40D and no transgene insertion at 30B and enables researchers to easily test whether their genetic screen of interest will be affected by ectopic tiptop expression.

4 further KK lines were created by meiotic recombination to separate the insertions at 30B and 40D. These lines contain an insertion of the UAS-RNAi construct in the landing site at 30B only and no insertion at the 40D landing site.
VDRC_ID 111000 is the "30D only" version of VDRC_ID 107151 (CG8208, MBD-like)
VDRC_ID 111001 is the "30D only" version of VDRC_ID 104523 (CG4005, Yki)
VDRC_ID 111002 is the "30D only" version of VDRC_ID 106174 (CG12072, Wts)
VDRC_ID 111003 is the "30D only" version of VDRC_ID 105838 (CG4236, Caf1)

When using these lines, please reference Vissers et al (2016) and acknowledge the VDRC for providing the lines.

Your VDRC Team

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RNAi collection extended – new shRNA lines added (Apr. 18, 2016)

Dear VDRC users,

The Vienna Drosophila Resource Center is pleased to announce a collection of new UAS-RNAi lines using short hairpin microRNA (shRNA) technology to extend and complement the current VDRC RNAi collection. Nearly 200 new lines are already available (www.vdrc.at) and a further 300 lines, currently in the VDRC production pipeline, will be made available to the community as soon as they are ready.

For commonly studied genes, where there is only 1 RNAi line in the VDRC GD or KK collection at present, we aim to add a further functional RNAi line to facilitate verification of phenotypes.

We have used shRNA technology to create these lines, as used extensively by the Transgenic RNAi Project (TRiP) and have collaborated with the TRiP team for hairpin design. The VDRC shRNA lines are consistent with, and complementary to, the TRiP shRNA lines, but the shRNAs target mRNA sequences which are independent of all current resources. The new collection therefore extends the range of RNAi lines available to the Drosophila research community.

For further details, see here.

Your VDRC Team

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New stocks added from Brennecke group (Feb. 18, 2016)

Dear VDRC users,

Our collection of "Other Resources" is growing and we have now added 175 stocks provided by Julius Brennecke (IMBA, Vienna). The new collection contains a variety of published stocks including 60 RNAi lines plus mutant alleles, tagged constructs, reporters, piRNA biogenesis reporters, miRNA sensors and tethering lines.

VDRC is open to donations of highly used stocks for integration into its community stock center collection. In addition, we offer a Private Stock Keeping Service where we will maintain and distribute your personal fly stock/plasmid collection on your behalf. See the Policy for VDRC Stock Keeping Services section for more information.

If you wish to donate resources to VDRC or use our Private Stock Keeping Service, please contact us (office@vdrc.at) to discuss as early as possible.

Your VDRC Team


KK landing site update (Jan. 14, 2016)

Dear VDRC users,

The Vienna Drosophila Resource Center (VDRC) would like to inform you of a recent publication regarding the KK RNAi library and a new stock for control experiments: KK Library Reliability

Your VDRC Team

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VDRC host institute name change (Jan. 01, 2016)

Dear VDRC users,

As of 1st Jan 2016, the VDRC host institute will change its name from "Campus Science Support Facilities GmbH" (CSF) to "Vienna Biocenter Core Facilities GmbH" (VBCF).

All VDRC services will continue exactly as before, with the only change being that invoices will be issued by VBCF. All bank details remain unchanged.

Your VDRC Team

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